Arizona Cardinals at San Francisco 49ers odds, expert picks, how to watch: Niners are biggest Week 5 favorites
49ers Hope to Build Momentum Against Cardinals in Week 5 #
The San Francisco 49ers are looking to build on their recent success as they prepare to face the Arizona Cardinals in a divisional clash on Sunday. Despite an inconsistent start to the season due to injuries, the defending NFC champions are currently the biggest favorites in Week 5.
The 49ers (2-2) showed improvement in their convincing 30-13 win over New England last week, with key players returning to action. The team’s quarterback benefited from the return of two important offensive weapons, while the running game continued to perform well in the absence of their star running back.
However, one key offensive player remains questionable for Sunday’s game.
The Cardinals (1-3) have struggled defensively in recent weeks, losing to the Detroit Lions and Washington Commanders after a strong performance against the Rams in Week 2. Their defense allowed 42 points in last week’s loss to Washington.
Both teams have had difficulties stopping opponents on third down, with conversion rates hovering around 46%. The 49ers’ defense, however, has shown more overall resistance and recently recorded six sacks and three turnovers against the Patriots.
An All-Pro linebacker for the 49ers left last week’s game with an ankle injury after scoring a defensive touchdown, but the injury is not considered serious. This potential return to health could spell trouble for the Cardinals, who have lost four consecutive games against their NFC West rivals.
The game will take place at Levi’s Stadium in Santa Clara, California, with kickoff scheduled for 4:05 p.m. ET. It will be broadcast on FOX and available for streaming.
As the 49ers aim to overcome their early-season challenges and the Cardinals seek to improve their defensive performance, this divisional matchup promises to be an intriguing contest in Week 5 of the NFL season.